in komplete kontrol and native access on an other directory than C: for example I:
Please use latest version of Native Access for your OS .
Yes , you can change both the Download directory and the Content Directory in the N.A. File Management settings. However then please leave Applications path at the default.
Please check this support article for general information about using Native Access : Using Native Access
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@StefDrop Not sure x-what you mean here and what you're asking, maybe a few more details on what you are trying to achieve would help.
Just to be crystal clear, the location where you install your individual addon products is determined in Native Access as shown above in @PoorFellow 's post. If you're asking about whether you can move the Native Access and Komplete Kontrol programs to a different drive location than your system drive, that's a much more complex situation. If you're initially installing them you might be okay to install them on a different internal drive connected directly to your motherboard. But there are a LOT of considerations here and you'd be MUCH better off describing your situation and the specifics about the computer your working with if you want to be sure about making the best choices.