After NA insisted on updating itself to 3.22 I've been having problems.
It showed me 4 updates, but gave me "Failed" messages on all of them.
I tried rebooting, then downgrading NA, running as administrator (which I do anyway) but it stayed the same.
All I can see now is an update to Komplete Kontrol v2.91, I currently have KK2.9. As soon as I try to update I get this message as in the attached screen shot. Everything else is working OK.
Windows 10 fully updated