I'm using the newest Version of Fl Studio, but tbh it doesn't really matter* what version I use since this problem existed ever since I first started using Reaktor. Sometimes I tweak and programm for hours on Reaktor patches and then save the Project file in my DAW. To my suprise, all my changes have been completly discarded every time. Since I usually start with a preset from "Reaktor Blocks" f.e. "Quadrapolis.ens" and change a Patch, tweak for an hour or two and change stuff, everything is gone once I saved and reload the project file. This is even the case for if I manually save with "File" --> "Save Preset as...".
*I already tried to ask the support for this problem a year or two ago. They basically just told me go tell this issue to Image Line since this isn't a Problem Native Instruments has to fix (???). I'm not sorry for saying this, I paid over 1500€ on your guys's software. The least I can expect is for the programm to work as expected.