Hi,
I have been having random disconnects of my USB hardware on my Apple silicon machine for a couple of months. Through this process, I replaced my USB hub with a Thunderbolt one, I have replaced many of my USB cables to no avail.
After finally contacting Apple support, I ran my machine in Safe Mode for a day without any issues.
Knowing that the issue is software, and not hardware, I went systematically through all the start-up items on my system until I found that disabling NIHostIntegrationAgent and NIHardwareAgent finally stopped the issue.
Given this is not currently supported on Apple silicon, I can't blame anyone but myself. Nevertheless, re-posting in case others face similar.
Hopefully once Native Instruments certifies their hardware/software on Apple silicon this issue will disappear.