I am up to date on software updates from what I can tell, running Komplete Audio 2 into MBP M2 Pro, Sonoma 14.1.1
My interface shows there is signal (LEDs light up) going in from the guitar cable. It works fine with Guitar Rig 6 Player, but nothing with Guitar Rig 7 LE v7.0.2 (no signal, nothing getting to its tuner or amp sims, etc.). File/Preferences/Audio has been set to Komplete Audio 2 (interface) and Input 1 (marked "IN 1" on the hardware) where the cable is plugged in.
Guitar Rig 5 works too.