Change of Software base

If you copy everything from one drive to another and retains all directory names and directory structures and then after having attached the new drive gives the new drive the same drive letter as the old drive then it usually works as if it had been the other drive.

Else : Moving a Native Instruments Product to Another Location on Your Computer

Using the Repair / Relocate All Function in Native Access

As for the drive sharing then I would imagine that in some case it would work , however in other cases it might not since if you update the libraries on one computer then that might create a data inconsistency with the other setup , but never having used such a setup I couldn't say for sure.